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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK18
All Species:
24.55
Human Site:
Y253
Identified Species:
45
UniProt:
Q07002
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07002
NP_002587.2
472
54180
Y253
Q
L
L
R
G
L
A
Y
C
H
H
R
K
I
L
Chimpanzee
Pan troglodytes
XP_521035
762
83144
Y542
Q
L
L
R
G
L
A
Y
C
H
R
Q
K
V
L
Rhesus Macaque
Macaca mulatta
XP_001100911
485
54881
Y265
Q
L
L
R
G
L
A
Y
C
H
R
Q
K
V
L
Dog
Lupus familis
XP_539731
541
61618
Y321
E
F
L
R
G
W
A
Y
C
T
E
N
K
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q04899
451
51829
Y232
Q
L
L
R
G
L
A
Y
C
H
H
R
K
I
L
Rat
Rattus norvegicus
O35832
451
51863
Y232
Q
L
L
R
G
L
A
Y
C
H
R
R
K
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510894
523
59528
Y303
Q
I
L
R
G
L
A
Y
C
H
R
R
K
V
L
Chicken
Gallus gallus
XP_001234978
430
49073
E231
P
Q
N
L
L
I
N
E
R
G
E
L
K
L
A
Frog
Xenopus laevis
Q6DJM7
435
49211
I230
L
K
P
Q
N
L
L
I
S
D
T
G
E
L
K
Zebra Danio
Brachydanio rerio
Q1RLU9
418
47889
D223
L
G
E
L
K
L
A
D
F
G
L
A
R
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48609
294
33162
D99
D
S
L
N
G
E
I
D
M
A
V
C
R
S
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
K99
D
S
C
P
E
F
A
K
N
P
T
L
I
K
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
K99
D
S
T
P
D
F
S
K
D
L
H
M
I
K
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.3
61.4
61.3
N.A.
87.7
88.1
N.A.
63.8
76.4
46.1
43.8
N.A.
34.1
N.A.
N.A.
N.A.
Protein Similarity:
100
53.1
75.2
73.9
N.A.
92.5
92.8
N.A.
77.4
81.9
61.6
57.4
N.A.
44
N.A.
N.A.
N.A.
P-Site Identity:
100
80
80
53.3
N.A.
100
93.3
N.A.
80
6.6
6.6
13.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
66.6
N.A.
100
93.3
N.A.
93.3
20
26.6
20
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
33
N.A.
33.2
N.A.
N.A.
Protein Similarity:
N.A.
47
N.A.
47.8
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
70
0
0
8
0
8
0
0
8
% A
% Cys:
0
0
8
0
0
0
0
0
54
0
0
8
0
0
0
% C
% Asp:
24
0
0
0
8
0
0
16
8
8
0
0
0
0
0
% D
% Glu:
8
0
8
0
8
8
0
8
0
0
16
0
8
0
0
% E
% Phe:
0
8
0
0
0
16
0
0
8
0
0
0
0
0
8
% F
% Gly:
0
8
0
0
62
0
0
0
0
16
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
47
24
0
0
0
0
% H
% Ile:
0
8
0
0
0
8
8
8
0
0
0
0
16
24
0
% I
% Lys:
0
8
0
0
8
0
0
16
0
0
0
0
62
16
16
% K
% Leu:
16
39
62
16
8
62
8
0
0
8
8
16
0
16
54
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% M
% Asn:
0
0
8
8
8
0
8
0
8
0
0
8
0
0
0
% N
% Pro:
8
0
8
16
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
47
8
0
8
0
0
0
0
0
0
0
16
0
0
0
% Q
% Arg:
0
0
0
54
0
0
0
0
8
0
31
31
16
0
0
% R
% Ser:
0
24
0
0
0
0
8
0
8
0
0
0
0
16
8
% S
% Thr:
0
0
8
0
0
0
0
0
0
8
16
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
31
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _